Hematological and biochemical changes following Ivermectin treatment in mange infested goats
AL-Qadisiyah Journal of Veterinary Medicine Sciences,
2015, Volume 14, Issue 1, Pages 69-74
AbstractThe aim of the present study was to describe the clinical features of mange and to evaluate the effectiveness of Ivermectin in treatment of affected goats referring to hematological and biochemical aspects. For this purposes local 180 female goats (does) kept in Farm Animal-College of Veterinary Medicine-Baghdad University were examined. Their ages were (1-2) years and had a mean average weight of (27.50 ± 2.25) kg. Thirty-six goats out of 180 were infested with mange. Other 36 was chosen from the herd and regarded as a control group. The infested group received Ivermectin 1% injected by subcutaneous route at a dose rate of 0.2 mg/kg B.W., in a single dose, while the control group received none. Blood samples were collected aseptically via jugular vein puncture at zero time, as well as 28 days post-Ivermectin treatment. Results indicated that the causative agent was Sarcoptis scabiei var caprae with a percent of 20% which were noticed on the muzzle, ears, neck, face, shoulder and back. White blood cells (WBCs) were increased in the untreated goats compared with the treated goats after 28 days of the experiment. Red blood cells (RBCs), hemoglobin (Hb) content and packed cells volume (PCV) increased significantly (p< 0.05) at four weeks after the commencement of treatment. Total protein, albumin, globulin, bilirubin and glucose were significantly decreased (p< 0.05) in untreated group compared with treatment and control groups. In conclusion, the treatment goats were much more active and had gone back to feed with the absence of lesion after 28 days post-treatment beside retaining the hematological and biochemical parameters to nearly normal values..
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